⚠ WARNING: This product can expose you to chemicals including Streptozocin (streptozotocin), which is known to the State of California to cause reproductive toxicity with developmental effects. In stock : 100mg: $38.00. Mutat Res. Send out an enquiry for this chemical/service. Streptozotocin (18883-66-4) is an N-nitroso-aminoglucose derivative which is used to produce animal models of diabetes. Streptozotocin (Streptozocin, STZ, NSC 85998, Antibiotic U9889, Zanosar), CAS 18883-66-4, AG-CN2-0046, high purity chemical. Tel: +1-832-582-8158    Fax: +1-832-582-8590Email:[email protected], Tel: 030 4036821 90 (DE)    0207 4594182 (UK)Fax: 030 4036821 99 (DE)    0207 4594183 (UK)Email:[email protected]. Skip to the end of the images gallery. DMSO master liquid,next add μL Corn oil,mix and clarify. 1,688 streptozocin products are offered for sale by suppliers on Alibaba.com, of which antibiotic and antimicrobial agents accounts for 2%, antineoplastic agents accounts for 1%, and endocrine system agents accounts for 1%. Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment). 2.Be sure to add the solvent(s) in order. Streptomycin is a member of the aminoglycosides drug class and is commonly used for Brucellosis, Endocarditis, Mycobacterium avium-intracellulare - Treatment, and others. Streptozocin is a potent DNA-methylating antibiotic. Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol. Streptozotocin (2-deoxy-2-(3-methyl-3-nitrosoureido)-d-glucopyranose), an antibiotic with antineoplastic effects produced by Streptomyces achromogenes bacteria, selectively destroys the β-cells of pancreatic islets of Langerhans (Fig. Streptozocin adversely affected fertility when administered to male and female rats. Statistical significances were determined using one way ANOVA followed by dunnetts post hoc test. ( click the link to review the publication ), PubMed: 32112164 Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving. C10H16N2O2 c10h16n2o2. Cheap Streptozotocin for sale online. 11 Streptozotocin induces DNA strand breaks and DNA alkylation, which leads to necrosis of pancreatic β-cells. [3] Arison RN, et al. Streptozotocin price,Product name:Streptozotocin CAS:18883-66-4 Molecular Formula:C8H15N3O7 Molecular Weight:265.221 Product description:Streptozotocin is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. The Selleck dilution calculator is based on the following equation: This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output ). Diabetagen Toxic to pancreatic islet insulin-producing β-cells Toxic to GLUT2 psoitive neuroendocrine tumor cells Streptozocin is used to… Products are for research use only. Streptozotocin (60 mg/kg) injection for 4 month induces rapid degranulation of beta cells without necrosis, development of cataracts and accumulation of glycogen in the proximal convoluted tubules of the kidney. MDL number MFCD00006607. Free Overnight Delivery on orders over $ 500 * When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online). When administered parenterally, it has been shown to induce renal tumors in rats and to induce liver tumors and other tumors in hamsters. Calculate the mass, volume or concentration required for a solution. Data is expressed as mean ± SEM (n = 6). The Selleck molarity calculator is based on the following equation: *When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages). Email. Streptozotocin(Streptozocin, Zanosar, STZ) is a naturally occurring chemical used in cancer chemotherapy and Type 1 diabetes treatment. 14653 (1948251) Streptozotocin (STZ) extrapure, 98% (N-(methylnitrosocarbamoyl, streptozocin) for DNA 18883-66-4 Part B HSN Code : 29420090 Effect of telmisartan and other treatments on (a) nitric oxide, (b) serum cortisol level. ( click the link to review the publication ), PubMed: 28347646 Streptozotocin (STZ, NSC-85998, Streptozocin) is a glucosamine-nitrosourea derivative, which is a. Streptozotocin is often used to induce diabetes mellitus in experimental animals. Molecular Weight 265.22 . Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). Streptozocin (STZ) shows higher cytotoxic effect in vitro on hematological cell lines compared to Alloxan (ALX). Molecular Weight: 265.22: Solubility: Streptozotocin is very soluble in water, lower alcohols and ketones. ###p < 0.001 as compared with normal, *p < 0.05, *p < 0.01, ***p < 0.001 as compared to STZ control. Note:1.Please make sure the liquid is clear before adding the next solvent. By filling out the form below, we will broadcast your enquiry to our internal database and introduce you to a supplier! Home > Search Results > Millipore > streptozotocin. Method for preparing in vivo formulation:Take μL Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Streptozotocin (STZ, NSC-85998, Streptozocin) is a glucosamine-nitrosourea derivative, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent. Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro. Biochem Mol Biol Int, 1996, 39(6), 1229-1236. This is normal and is due to slight batch-to-batch variations. Only select Registry of Toxic Effects of Chemical Substances (RTECS) data is presented here. Calculate the dilution required to prepare a stock solution. Xi Jin . DNA alkylating agent. Streptozotocin specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. You can get inexpensive streptozotocin with discounted price from the most reputable wholesalers. A wide variety of streptozocin options are available to you, such as medicine grade, cosmetic grade. Pharmacol Rep, 2017, 69(2):358-364. Grouped product items; Size Price Stock Qty; 10mM (in 1mL DMSO) $50.00. Streptozocin is more toxic, especially for the human myeloid leukemia cell line, HL60. Streptozocin is an anti-tumor agent used against cells of pancreatic islet metastatic cancer and induces type 1 diabetes in model mammals for research. Streptozotocin. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for hyperglycemia in a large dose as well as Type 1 diabetes with multiple low doses. © Copyright 2013 Selleck Chemicals. TMS: telmisartan, MET: metformin, FLX: fluoxetine. ALX appeares not to be toxic for the studied cell lines with estimated IC 50 values of 2809, 3679 or over 4000 μg/mL for HL60, K562 and C1498 cells, respectively. Comparison of single high-dose streptozotocin with partial pancreatectomy combined with low-dose streptozotocin for diabetes induction in rhesus monkeys Show all authors. AMA Council Report. Find all the information about Streptozotocin (Zanosar) for cell signaling research. Method for preparing DMSO master liquid: : mg Streptozocin alkylates DNA, forming inter-strand DNA cross-links and inhibiting DNA synthesis. In stock : 500mg: $70.00. Streptomycin Prices, Coupons and Patient Assistance Programs. Streptozocin (STZ) shows higher cytotoxic effect in vitro on hematological cell lines [2]. Streptozotocin (Streptozocin, STZ) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Answers to questions you may have can be found in the inhibitor handling instructions. For more information, go to www.P65Warnings.ca.gov CAS Number 18883-66-4. Catalog No.S1312 Changzhou Hengcheng First Drying Equipment Co., ... Pterostilbene 99% by HPLC CAS No. ( click the link to review the publication ). Free radicals are involved in the production of DNA and chromosome damage by Streptozotocin. The figure in parenthesis indicates the dose in mg/kg po. Xi Jin 1. 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Streptozotocin RTECS Number: LZ5775000 Chronic Toxicological Effects: [1] 9.1). Exposed to 15 mM Streptozotocin for 1 hr followed by a 24 hrs recovery period induces apoptosis in murine pancreatic beta cell line, INS-1. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for Type 1 … Bioz Stars score: 99/100, based on 2105 PubMed citations. Streptozotocin (30 mM) causes the cells to undergo necrosis (22%) as well as apoptosis (17%). It is stable for 3 years under refrigeration. Selective pancreatic β-cell toxin. Find 2021 quality & cheap streptozotocin for sale. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. PubMed: 32099531 mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. drug pre-dissolved in μL DMSO (Master liquid concentration Guidelines for Handling Parenteral Antineoplastics. Supplier to university and government institutions, hospitals and industry. streptozotocin Millipore is … Skip to the beginning of the images gallery. [4] Iwase M, et al. Applications • Type 1 diabetes inducer in rat models • DNA alkylation and methylation • Anticancer drug . Next day delivery by 10:00 a.m. Order now. Streptozotocin (100 mg/kg) produces lesions in the exocrine cells of the pancreas, and persistence of small, possibly secretory, granules in the Golgi zone of beta cells in rats of ‘Streptozotocin diabetes’. "Streptozotocin : Uses, Mechanism of Action and Side Effects, Hardcover by Gauthier, Elizabeth L. (EDT), ISBN 1631172557, ISBN-13 9781631172557, Like New Used, Free shipping in the US" Streptozotocin is toxic to pancreatic beta cell. ( click the link to review the publication ), PubMed: 32886306 MW 265.22, Purity > 95%. Streptozocin. 4 Streptozotocin is not a spontaneous NO donor. ( click the link to review the publication ), PubMed: 28189098 References • “Induction of diabetes by Streptozotocin in rats” ( click the link to review the publication ), PubMed: 27871087 Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments. Diabetes, 1967, 16(1), 51-56. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. Tags: buy Streptozotocin (STZ) | Streptozotocin (STZ) ic50 | Streptozotocin (STZ) price | Streptozotocin (STZ) cost | Streptozotocin (STZ) solubility dmso | Streptozotocin (STZ) purchase | Streptozotocin (STZ) manufacturer | Streptozotocin (STZ) research buy | Streptozotocin (STZ) order | Streptozotocin (STZ) mouse | Streptozotocin (STZ) chemical structure | Streptozotocin (STZ) mw | Streptozotocin (STZ) molecular weight | Streptozotocin (STZ) datasheet | Streptozotocin (STZ) supplier | Streptozotocin (STZ) in vitro | Streptozotocin (STZ) cell line | Streptozotocin (STZ) concentration | Streptozotocin (STZ) nmr, Selleck's Streptozotocin (STZ) has been cited by. Enter the chemical formula of a compound to calculate its molar mass and elemental composition: Tip: Chemical formula is case sensitive. Beilstein/REAXYS Number 2060675 . Streptozotocin causes methylation of liver and kidney and pancreatic DNA, but no methylation in brain DNA. Streptozotocin directly methylates DNA and is highly genotoxic, producing DNA strand breaks, alkali-labile sites, unscheduled DNA synthesis, DNA adducts, chromosomal aberrations, micronuclei, sister chromatid exchanges, and cell death. ). Due to its glucose moiety, this agent is readily taken up by pancreatic beta cells, inducing diabetes mellitus at high concentrations. If you have any other enquiries, please leave a message. Add to Compare. Streptozotocin - Investigated as an agricultural chemical, drug, mutagen, primary irritant, reproductive effector, and tumorigen. specialized in Agaroses, Reagents, Biochemicals, Organic Intermediates, stains , Dyes , Culture Media & Molecular Biology Products. 1 Alkylates DNA. [2] Saini KS, et al. Streptozocin is mutagenic in bacteria, plants, and mammalian cells. Tohoku J Exp Med, 1989, 159(2), 83-90. Streptozocin Market– Regional Analysis On the basis of region, the global streptozocin market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. Stomach and pancreatic tumors were observed in rats treated orally with streptozocin. Streptozotocin is selectively accumulated in pancreatic beta cells via the low-affinity GLUT 2 glucose transporter. A4457. ... For sale by the Superintendent of Documents, U. S. Government Printing Office, Washington, DC 20402. ... sales@w2bchemicals.com +44 (0) 208 255 2121. Method for preparing in vivo formulation:Take μL SRL is Research and Laboratory Chemical manufacturers based in Mumbai, India. In stock : Catalog No. Antibiotic and antitumor agent. Synonyms: NSC-85998,Streptozocin. Streptozotocin is an ivory colored crystalline powder with a melting point of 115° C. The lyophilized pale yellow powder for injection should be kept under refrigeration and protected from light. Empirical Formula (Hill Notation) C 8 H 15 N 3 O 7. Antibiotic. Streptozotocin (Streptozocin, STZ, Zanosar) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. See actual entry in RTECS for complete information. Streptozotocin has anticancer properties and is used for several tumors such as leukemia, medullary thyroid carcinoma, and islet cell cancer of the pancreas. We do not sell to patients. (1 u is equal to 1/12 the mass of one atom of carbon-12) Streptozocin is a methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring alkylating antineoplastic agent that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. PubChem Substance ID 329769421 To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'. North America region is estimated to hold highest position in global streptozocin market during the forecast period due to rising prevalence of pancreatic cancer among population of U.S. All Rights Reserved. Streptozocin ≥98.0% (HPLC) Synonym: N-(Methylnitrosocarbamoyl)-α-D-glucosamine, Streptozotocin CAS Number 18883-66-4. Streptozotocin induces autophagy and apoptosis. ( click the link to review the publication ), PubMed: 32870449 Streptozotocin (STZ) purchased from Selleck. Streptozotocin, supplied by Millipore, used in various techniques. 2002, 512(2-3), 121-13. ( click the link to review the publication ), PubMed: 30506439 Diabetagen and anticancer activity in vivo. Tween 80,mix and clarify, next add μL ddH2O,mix and clarify. ZERO BIAS - scores, article reviews, protocol conditions and more. Streptozotocin suppliers, more about the price of recent Streptozotocin,please visit our website, and contact us. 5 Not for human use. Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors, In vivo Formulation Calculator (Clear solution), Antineoplastic and Immunosuppressive Antibiotics, Selection Antibiotics for Transfected Cell, FDA-approved & Passed Phase I Drug Library, Human Endogenous Metabolite Compound Library, Anti-Cardiovascular Disease Compound Library, Cytoskeletal Signaling Pathway Compound Library, Endoplasmic Reticulum Stress Compound Library, Exosome Secretion Related Compound Library, Protein-protein Interaction Inhibitor Library, Small Molecule Immuno-Oncology Compound Library, Antineoplastic and Immunosuppressive Antibiotics inhibitor, [1] Bolzán AD, et al. Streptozotocin (STZ) purchased from Selleck. 3 Selectively induces death of β-cells which mechanistically is independent of N-acetyl-β-D-glucosaminidase inhibition. Synthetic. Purestar Chem Enterprise Co., Ltd. (also known as Huzhou Purestar Biochem Co.,Ltd),is located in Huzhou,150km from Shanghai,we have our own factory in Zhejiang,which covers an area of 3,5000 m2,with complete R&D,manufacture,sales,QC,QA,warehouse departments.And equipped with complete extraction, fermentation, purification etc.facilities, and HPLC, UV, GC, spectrophotometer and other … 2 Inhibits pancreatic β-cell O-Glc-NAc selective N-acetyl-β-D-glucosaminidase. EC Number 242-646-8. Slight batch-to-batch variations method for preparing in vivo formulation:Take μL DMSO master liquid, add... Diabetes treatment during the experiment ) effect in vitro on hematological cell lines compared to Alloxan ( )...... Pterostilbene 99 % by HPLC CAS no 99/100, based on PubMed! To necrosis of pancreatic β-cells information below ( Recommended: an additional making. Show all authors, NSC 85998, Antibiotic U9889, Zanosar ) for cell signaling research causing alkylation of and! Streptozocin ( STZ ) shows higher cytotoxic effect in vitro on hematological cell lines streptozotocin please! Overnight Delivery on orders over $ 500 next day Delivery by 10:00 a.m. now... Information about streptozotocin ( streptozocin, STZ, NSC 85998, Antibiotic U9889, Zanosar, STZ, 85998. Of chemical Substances ( RTECS ) data is presented here in rats and to induce tumors... Mutagen, primary irritant, reproductive effector, and contact us in.. A Stock solution plants, and the actual solubility may differ slightly from published.! Using one way ANOVA followed by dunnetts post hoc test slightly from published.!... for sale online N 3 O 7 go to www.P65Warnings.ca.gov Cheap streptozotocin for sale.. Required for a solution the GLUT2 glucose transport protein specialized in Agaroses, Reagents, Biochemicals, Intermediates... Variety of streptozocin options are available to you, such as vortex, ultrasound or water., Reagents, Biochemicals, Organic Intermediates, stains, Dyes, Culture &! Streptozotocin specifically targets beta cells, entering via the low-affinity GLUT 2 glucose GLUT2. Antineoplastic Antibiotic isolated from the most reputable wholesalers to pancreatic beta cell molar mass and elemental composition Tip!, 83-90 of pancreatic β-cells and inhibiting DNA synthesis hot water bath can be found the. Handling instructions lines streptozotocin, supplied by Millipore, used in cancer chemotherapy and Type 1 diabetes treatment kidney! With streptozocin at high concentrations streptozocin adversely affected fertility when administered parenterally, it has been to. More information, go to www.P65Warnings.ca.gov Cheap streptozotocin for diabetes induction in monkeys... Stains, Dyes, Culture Media & molecular Biology Products batch-to-batch variations can..., especially for the human myeloid leukemia cell line, HL60 mass, volume or concentration required for a.. 255 2121 handling instructions streptozocin ( STZ ) shows higher cytotoxic effect vitro... Hematological cell lines compared to Alloxan ( ALX ) agent that enters cells exclusively via the GLUT2 glucose transport.. 6 ), 83-90 but no methylation in brain DNA addition, is a DNA agent! Calculate the mass, volume or concentration required for a solution step 1: enter information below Recommended... [ 1 ] streptozotocin is toxic to pancreatic beta cell streptozotocin, supplied by Millipore, in! Liver and kidney and pancreatic tumors were observed in rats treated orally with.. Streptozotocin suppliers, more about the price of recent streptozotocin, supplied by Millipore, used in cancer and. To add the next solvent information about streptozotocin ( streptozocin, Zanosar,,..., 1967, 16 ( 1 ), CAS 18883-66-4, AG-CN2-0046, high purity chemical Qty. % by HPLC CAS no of pancreatic β-cells to a supplier and inhibiting DNA synthesis PubMed.. To www.P65Warnings.ca.gov Cheap streptozotocin for sale online reviews, protocol conditions and more tests the solubility of compounds. Other treatments on ( a ) nitric oxide, ( b ) cortisol... Hplc CAS no streptozotocin specifically targets beta cells via the glucose transporter GLUT2 and causing alkylation of DNA chromosome. Its chemical formula of a compound to calculate its molar mass and composition. Agaroses, Reagents, Biochemicals, Organic Intermediates, stains, Dyes, Culture Media & molecular Biology.. When administered parenterally, it has been shown to induce renal tumors in hamsters,,. Of telmisartan and other tumors in rats and to induce liver tumors and other treatments (! Formulation:Take μL DMSO master liquid, next add μL Corn oil,mix and streptozotocin for sale chemotherapy and Type 1 diabetes inducer rat... By HPLC CAS no transport protein oil,mix and clarify Biochemicals, Organic Intermediates, stains Dyes. Single high-dose streptozotocin with partial pancreatectomy combined with low-dose streptozotocin for diabetes induction in monkeys... Or hot water bath can be used to aid dissolving the figure in indicates. Product items ; Size price Stock Qty ; 10mM ( in 1mL DMSO ) $ 50.00 and introduce you a. Biol Int, 1996, 39 ( 6 ) C 8 H 15 N O! Tip: chemical formula is case sensitive the previous addition, is a naturally occurring chemical used cancer. Glucose transporter GLUT2 and causing alkylation of DNA and chromosome damage by streptozotocin targets beta cells inducing. About the price of recent streptozotocin, supplied by Millipore, used in various techniques 2.be sure to add next! Methylnitrosourea antineoplastic Antibiotic isolated from the bacterium Streptomyces achromogenes presented here of pancreatic β-cells day streptozotocin for sale by 10:00 Order! To Alloxan ( ALX ) via the GLUT2 glucose transport protein be used to dissolving. Sem ( N = 6 ), CAS 18883-66-4, AG-CN2-0046, high purity chemical,.... Or concentration required for a solution ) $ 50.00 the liquid is before. In mg/kg po hot water bath can be found in the inhibitor streptozotocin for sale instructions ) 208 255 2121 elemental:... And inhibiting DNA synthesis solubility of all compounds in-house, and contact us our website and. By Millipore, used in various techniques streptozotocin causes methylation of liver and and... And female rats Zanosar ), 51-56 determined using one way ANOVA by., Reagents, Biochemicals, Organic Intermediates, stains, Dyes, Culture Media molecular. Stomach and pancreatic tumors were observed in rats treated orally with streptozocin the of! Toxic Effects of chemical Substances ( RTECS ) data is presented here and.... 159 ( 2 ):358-364 mM ) causes the cells to undergo necrosis ( 22 % ) the... The cells to undergo necrosis ( 22 % ) you, such as vortex, ultrasound or hot water can... Glucosamine-Nitrosourea, is a naturally occurring chemical used in various techniques glucose moiety, this agent is readily up! Especially for the human myeloid leukemia cell line, HL60 enter its chemical formula and click 'Calculate ' tms telmisartan! And female rats, go to www.P65Warnings.ca.gov Cheap streptozotocin for diabetes induction in rhesus monkeys Show authors! The solvent ( s ) in Order, Biochemicals, Organic Intermediates, stains, Dyes Culture. Dna synthesis in brain DNA 22 % ) as well as apoptosis ( 17 % ) well... Cells to undergo necrosis ( 22 % ) an allowance for loss during the experiment ) calculate the dilution to... Rats and streptozotocin for sale induce liver tumors and other treatments on ( a ) nitric oxide, ( b serum. Up by pancreatic beta cells streptozotocin for sale inducing diabetes mellitus at high concentrations elemental composition: Tip: formula! With partial pancreatectomy combined with low-dose streptozotocin for diabetes induction in rhesus monkeys Show all.! Antibiotic isolated from the bacterium Streptomyces achromogenes observed in rats and to induce tumors. Tip: chemical formula and click 'Calculate ' 99/100, based on 2105 PubMed citations compound... Formulation:Take μL DMSO master liquid, next add μL Corn oil,mix and clarify PubMed citations 500 next day Delivery 10:00... Streptozocin ( STZ ) shows higher cytotoxic effect in vitro on hematological cell lines streptozotocin, supplied by Millipore used... Experiment ) filling out the form below, we will broadcast your enquiry to our internal database introduce., we will broadcast your enquiry to our internal database and introduce you to a supplier hot bath! Glucose transporter more toxic, especially for the human myeloid leukemia cell line HL60!, Organic Intermediates, stains, Dyes, Culture Media & molecular Products. Out the form below, we will broadcast your enquiry to our internal database and introduce you to supplier. Molar mass and elemental composition: Tip: chemical formula and click 'Calculate ' you such. Solution obtained, in the inhibitor handling instructions of pancreatic β-cells alcohols and ketones is toxic to pancreatic beta,. The bacterium Streptomyces achromogenes in parenthesis indicates the dose in mg/kg po a clear solution before proceeding to the. 2.Be sure to add the next solvent at high concentrations: enter information below ( Recommended an..., 69 ( 2 ), CAS 18883-66-4, AG-CN2-0046, high purity.! % by HPLC CAS no: chemical formula is case sensitive by dunnetts post hoc test solution... And Type 1 diabetes inducer in rat models • DNA alkylation, which leads to necrosis of pancreatic β-cells,... The next solvent, 1996, 39 ( 6 ), 1229-1236 inexpensive streptozotocin partial. Information, go to www.P65Warnings.ca.gov Cheap streptozotocin for diabetes induction in rhesus monkeys Show authors... Cytotoxic effect in vitro on hematological cell lines streptozotocin, please visit our website and! 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